Interobserver Variation Within Planning Target Volume and Organs at Risk in a Patient with Oropharyngeal Carcinoma: A Contouring Study with Anatomical Analysis.

ABSTRACT: Background: Despite the availability of contouring guidelines and advanced imaging modalities, interobserver variability (IOV) in the delineation of the planning target volume and organs at risk remains a critical factor influencing treatment quality in radiotherapy. The aim of this study was to examine variations in contour delineation with respect to anatomical landmarks, as well as differences in the inclusion of lymph node levels within the PTV. Methods: Ten senior radiation oncologists from six different institutions participated in the study and contoured PTV1, PTV2 and 16 OARs in a patient with oropharyngeal carcinoma. Interobserver variation was quantified by volume statistics such as mean, standard deviation (SD) and ranges, as well as using coefficient of variance (

SUBMITTER: Baier F 

PROVIDER: S-EPMC12840011 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature