Air Pollution and Preterm Birth: A Scoping Review Focused on Preterm Birth Phenotype and Specific Lengths of Gestation.

ABSTRACT: Background/Objectives: Air pollution is a recognized risk factor for preterm birth (PTB), a major cause of neonatal morbidity and mortality. The biological mechanisms underlying this association remain unclear, partly because PTB is a composite outcome that includes both spontaneous (sPTB, from preterm labor or rupture of membranes) and medically indicated (mPTB, for conditions such as preeclampsia or fetal growth restriction) subtypes. Additionally, PTB spans a range of gestational lengths from 20 to 36 completed weeks, which may reflect distinct etiologic pathways. Methods: This scoping review identified studies evaluating two pollutants strongly linked to PTB-particulate matter < 2.5 µm in diameter (PM_2.5) and nitrogen dioxide (NO₂)-in relation to PTB

SUBMITTER: Abellard L 

PROVIDER: S-EPMC12840119 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature