Functional soft tissue regeneration involving extremity tendons using ovine forestomach matrix grafts.

ABSTRACT: Soft tissue defects with exposed tendons present unique challenges in surgical reconstruction, as tendons are vulnerable to desiccation, infection, and necrosis. We present a single-center, retrospective case series of 10 patients with exposed tendons who underwent surgical reconstruction with ovine forestomach matrix (OFM) grafts. Medical records were reviewed to establish patient demographics, co-morbidities, injury characteristics, and post-operative outcomes. OFM grafts were applied for staged reconstruction, for closure via secondary intention, as implants with primary closure or fasciocutaneous flaps, and as a circumferential tendon-protective layer. The median time to granulation tissue coverage was 3 weeks (IQR: 2, 4), and to full epithelialization 4 weeks (IQR: 1, 6). The median f

SUBMITTER: Naphade S 

PROVIDER: S-EPMC12840582 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature