A Co-Expressed Cluster of Genes in the Anterior Brain of Female Crickets Activated by a Species-Specific Calling Song.

ABSTRACT: Crickets use the pulse pattern of the species-specific calling song as a primary cue for mate recognition. Here we combined transcriptome profiling of brain regions with network-based analyses in Gryllus bimaculatus exposed to silence or pulse trains known to elicit strong or weak phonotactic attraction. Acoustic stimulation triggered specific transcriptional changes in the brain, with the anterior protocerebrum showing the most pronounced and selective responses to the calling song pattern, characterized by enrichment in neuromodulatory and neurotransmitter-related pathways. Weighted gene co-expression analysis identified a specific cluster of highly co-expressed genes in the anterior brain (termed the calling song-responsive module) that responded selectively only to the calling s

SUBMITTER: Xiong S 

PROVIDER: S-EPMC12841516 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature