Predictors of One-Year Renal Function Decline in Type 2 Diabetes: Implications for Metabolic Target Management.

ABSTRACT: Background: Early decline in kidney function is a major complication of type 2 diabetes mellitus (T2DM). The extent to which achievement of glycemic, blood pressure, lipid, and weight targets influences short-term renal trajectories remains insufficiently characterized. Methods: We conducted a retrospective analysis of 125 T2DM patients who had baseline and 1-year follow-up eGFR measurements at the Mongolia Japan Hospital of the MNUMS during 2023-2024. Clinical and metabolic control was categorized using standard thresholds. Renal outcomes were assessed using absolute 1-year eGFR change and the occurrence of ≥30% decline. Results: Mean eGFR declined from 91.2 ± 24.1 to 88.4 ± 25.5 mL/min/1.73 m² over one year (mean change -3.77 ± 11.3 mL/min/1.73 m²

SUBMITTER: Batbold A 

PROVIDER: S-EPMC12841840 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature