Neurological Complications in Surgical Patients with Left-Sided Infective Endocarditis: Risk Factors, Prognosis, and Surgical Timing.

ABSTRACT:

Background

The aim of this study was to explore the baseline characteristics, risk factors, and prognosis of surgical patients with left-sided valvular infective endocarditis (IE) complicated by preoperative neurological complications, as well as the impact of complication subtypes and surgical timing on outcomes.

Methods

A retrospective analysis of 605 consecutive surgical patients with left-sided valvular IE (May 2012-June 2024) was performed. Patients were stratified into neurological complication and non-complication groups, with 1:1 propensity score matching (PSM) balancing baseline confounders. Six neurological complication subtypes were defined; surgical timing was categorized as early (≤7 days for infarction, ≤30 days for hemorrhage) or delayed. Logistic/Cox regressi

SUBMITTER: Wu Z 

PROVIDER: S-EPMC12841926 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature