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Triple-Olfactory Mechanism Synergy: Development of a Long-Lasting DEET-Botanical Composite Repellent Against Aedes albopictus.


ABSTRACT: Mosquito-borne diseases, including dengue fever, chikungunya, and Zika, continue to pose a substantial global public health challenge. This is largely attributable to the absence of effective vaccines and the expanding distribution of vectors such as Aedes albopictus (Ae. albopictus). Repellents, therefore, remain a critical component of prevention strategies for disease prevention. However, existing formulations have notable limitations. Synthetic repellents such as DEET provide broad-spectrum efficacy but may raise safety concerns, especially at high concentrations. In contrast, botanical repellents, such as citronella and camphor oils, offer more favorable safety profiles but are restricted by short protection durations due to their high volatility. To overcome these drawb

SUBMITTER: Lin CX 

PROVIDER: S-EPMC12842024 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature