Predictors of Decision-Making Regarding Endocrine Therapy in Breast Cancer Survivors: A Systematic Review.

ABSTRACT: Background/Objectives: Endocrine therapy (ET) is a common treatment for hormone-dependent breast cancer and is associated with a significant reduction in recurrence and mortality rates. However, the decision to initiate endocrine therapy is a critical and often distressing juncture for patients. The need to weigh its survival benefits against the potential burden of side effects, including mood changes, pain, muscle stiffness, and fatigue, can render this decision-making phase a source of significant distress. The present systematic review aimed to identify and synthesize the sociodemographic and psychosocial predictors of the decision-making process related to ET adherence among women with breast cancer. Methods: A systematic literature search was conducted in three electron

SUBMITTER: Mesquita B 

PROVIDER: S-EPMC12842196 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature