Critical Assessment of Evidence Quality of Meta-Analyses Comparing Sacral 2 Alar-Iliac Fixation with Iliac Screws for Adult Spinal Deformity: An Umbrella Review with Emphasis on Methodological Limitations.

ABSTRACT: Background/Objectives: Adult spinal deformity (ASD) management often requires pelvic fixation, with S2 alar-iliac (S2AI) screws emerging as an alternative to traditional iliac screws. Despite multiple meta-analyses comparing these techniques, the methodological quality of these syntheses and technical heterogeneity across primary studies significantly impact their conclusions and subsequent clinical decision-making. This systematic review evaluates the evidence quality of meta-analyses comparing S2AI with traditional iliac screws for ASD management, focusing on methodological rigor, primary study overlap, and clinical heterogeneity. Methods: PubMed, Cochrane, and Epistemonikos were searched for meta-analyses comparing S2AI with iliac screws for patients with ASD. The Quality

SUBMITTER: Bangash AH 

PROVIDER: S-EPMC12842343 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature