Photo Crosslinkable Hybrid Hydrogels for High Fidelity Direct Write 3D Printing: Rheology, Curing Kinetics, and Bio-Scaffold Fabrication.

ABSTRACT: This work characterizes hybrid hydrogels prepared via the combination of natural and synthetic polymers. By incorporating a biocompatible compound, poly(ethylene glycol) diacrylate (PEGDA, M_n = 400), into alginate and carboxymethyl cellulose (CMC)-based hydrogels, the in situ UV crosslinking of these materials was assessed. A custom direct-write (DW) 3D bioprinter was utilized to prepare hybrid hydrogel constructs and scaffolds. A control sample, which consisted of 4% w/v alginate and 4% w/v CMC, was prepared and evaluated in addition to three PEGDA (4.5, 6.5, and 10% w/v)-containing hybrid hydrogels. Rotational rheology was utilized to evaluate the thixotropic behavior of these materials. Filament fusion tests were employed to generate

SUBMITTER: Rohauer R 

PROVIDER: S-EPMC12842536 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature