Combined Transcriptomic and Metabolomic Analyses of the Response of Ganoderma lucidum to Elevated CO₂.

ABSTRACT: Carbon dioxide (CO₂) is a key environmental factor that regulates the morphology of fruiting bodies in edible fungi. High CO₂ concentrations often lead to the formation of antler-shaped abnormal fruiting bodies in Ganoderma lucidum. Yet, the molecular response mechanisms underlying this process remain unclear. To address this gap, this study integrated transcriptomics and untargeted metabolomics to compare the transcriptional and metabolic profiles of G. lucidum fruiting bodies at three growth stages, cultivated under both normal (0.04%) and high CO₂ concentrations (0.3%). Metabolomic analysis revealed that, compared to the control groups, 387, 337, and 445 differentially accumulated metabolites were identified in the elevated-CO₂ g

SUBMITTER: Fang T 

PROVIDER: S-EPMC12842923 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature