Ninjin'yoeito for Impaired Oral Function in Older Adults: A Prospective, Open-Label Pilot Study.

ABSTRACT: Background and Objectives: Japan's aging population faces growing challenges related to oral frailty, a condition characterized by the decline of oral function associated with physical and nutritional deterioration. Impaired oral function contributes to reduced chewing, swallowing, and saliva secretion, leading to poor appetite and frailty progression. Ninjin'yoeito (NYT), a traditional Kampo formula, has been clinically used to improve systemic weakness and oral symptoms. This study aimed to evaluate the efficacy and safety of NYT in improving oral health among elderly individuals with impaired oral function. Materials and Methods: In this open-label prospective study, patients received NYT daily for 12 weeks. Assessments included oral symptom scores, mucosal moisture, repet

SUBMITTER: Ngo QT 

PROVIDER: S-EPMC12843259 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature