Skin graft bolstered by negative pressure therapy in chronic wounds: A systematic review.

ABSTRACT:

Background

Chronic ulcers represent a significant burden for patients, often requiring advanced therapeutic interventions. Skin grafting is a critical treatment option, yet the risk of graft failure remains substantial. Negative pressure wound therapy (NPWT) has demonstrated efficacy in enhancing graft survival in acute wounds, but its effectiveness in chronic ulcers remains underexplored.

Objectives

This systematic review aimed to evaluate the efficacy of NPWT in bolstering skin grafts for the treatment of chronic ulcers.

Methods

We conducted this systematic literature review using the scientific databases PUBMED, COCHRANE and EMBASE. Studies involving skin grafts supported by NPWT for chronic wounds were included, while those focussing on acute wounds, burns or post

SUBMITTER: Gamel M 

PROVIDER: S-EPMC12843873 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature