Dried Blood Spots Capture a Wide Range of Metabolic Pathways and Biological Characteristics Associated with Fish Oil Supplementation, Fasting, and the Postprandial State.

ABSTRACT:

Background

Metabolomics is recognized as crucial technology for advancing our ability to diagnose, characterize, and monitor treatment of disease. Yet, metabolomics-based diagnostic testing has not been widely adapted into clinical practice because its technical requirements make it generally incompatible with operation at the point of care. One way to expand the reach of metabolomics-based testing, and its clinical benefits, is to utilize dried blood spots (DBS) as a testing sample type. Their easy collection, ambient storage capability, and cost-effective shipment make DBSs ideal for diagnostic tests that require the use of a centralized technology.

Methods

To date, relatively few studies have investigated the performance of DBSs at capturing the global metabolome and repo

SUBMITTER: DeBalsi KL 

PROVIDER: S-EPMC12843892 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature