Genetic Diversity of Campylobacter concisus Isolates from Slovenian Patients with Infectious Diarrhoea.

ABSTRACT: Campylobacter concisus is recognized as a potential pathogen in gastrointestinal diseases, particularly in patients with chronic intestinal diseases. This study investigates the genomic characteristics, phylogenetic distribution, virulence factors, resistance genes and presence of plasmids in C. concisus isolates from Slovenian patients with community-acquired infectious diarrhoea. Prospectively collected isolates were analysed using whole-genome sequencing (WGS). WGS analysis revealed substantial genetic diversity among isolates, with distinct differences observed between two genomospecies (GS1, GS2). GS1 isolates had smaller genomes, lower GC content, and fewer coding regions than GS2 isolates. Multilocus sequence typing confirmed a high degree of genetic diversity, with mo

SUBMITTER: Kofol R 

PROVIDER: S-EPMC12844130 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature