Autotrophic and Mixotrophic Batch Processes with Clostridium autoethanogenum LAbrini in Stirred Tank Bioreactors with Continuous Gassing.

ABSTRACT: Simultaneous conversion of syngas and sugars is a promising approach to overcome limitations of syngas fermentation. Clostridium autoethanogenum LAbrini, obtained by adaptive laboratory evolution, is known to show improved autotrophic process performance. Under purely autotrophic conditions, C. autoethanogenum LAbrini exhibits substantially faster growth and biomass formation compared to the wild-type in fully controlled, stirred-tank bioreactors with a continuous gas supply. In mixotrophic processes, the pre-culture strategy has a significant impact on the growth and metabolic activity of C. autoethanogenum LAbrini. C. autoethanogenum LAbrini can metabolize sugars (D-fructose, D-xylose, or L-arabinose) and CO simultaneously. All mixotrophic batch processes show

SUBMITTER: Oppelt A 

PROVIDER: S-EPMC12844154 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature