Signaling Pathway Analysis and Downstream Genes Associated with Disease Resistance Mediated by GmSRC7.

ABSTRACT: GmSRC7 is a broad-spectrum antiviral R gene from soybean, but its downstream and functionally related genes remain unclear. Virus-induced gene silencing (VIGS) assays in Nicotiana benthamiana (Nb) showed that suppression of several gene families-WRKY transcription factors, chaperones, ethylene pathway components, MAPK cascade elements, salicylic acid (SA) signaling genes, calcium-dependent protein kinases, nuclear migration proteins, RNA replication-related genes, and immune regulators-consistently weakened GmSRC7-mediated resistance to Soybean Mosaic Virus (SMV) and Tobacco Mosaic Virus (TMV). Targeted silencing of four regulatory genes-NbEDS1, NbARF1, NbSGT1, and NbCOI1-markedly enhanced GmSRC7-mediated resistance to S

SUBMITTER: Li A 

PROVIDER: S-EPMC12845291 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature