Genomic Characterization of a Mycoplasma ovipneumoniae Strain from Hu Sheep in Inner Mongolia, China.

ABSTRACT: Mycoplasma ovipneumoniae poses a major threat to sheep respiratory health, contributing to significant economic losses in farming communities. In this study, we isolated a novel strain, IM-DMQ, from a Hu sheep in Inner Mongolia that exhibited pulmonary adenomatous-like lesions, which is an uncommon pathological manifestation for this pathogen. The complete genome was sequenced using a hybrid Nanopore and Illumina approach, revealing a 1,039,804 bp circular chromosome with a GC content of 29.15%, encoding 1529 genes. Functional annotation highlighted genes involved in essential metabolic processes and potential virulence mechanisms. Comparative genomic analysis demonstrated that IM-DMQ shares the closest ancestry (ANI: 98.3%) with the Chinese strain NXNK2203, while structural variati

SUBMITTER: Dai L 

PROVIDER: S-EPMC12846336 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature