Polymeric Hydrogels Loaded with ZnO Nanoparticles as Promising Tools for Tacking Viral Skin Disorders.

ABSTRACT: Zinc oxide nanoparticles (ZnO NPs) have attracted growing interest in several fields, including topical biomedical applications, due to their stability, biocompatibility and therapeutic potential. In this study, chitosan (Ch), gelatin (G) and arabic gum (AG) were combined to formulate hydrogels loaded with different ZnO NP concentrations. The main aim is to assess the synergy between the properties of biopolymers and ZnO moieties in terms of antiviral activity. ZnO NPs were synthesized via co-precipitation. Hydrogels were prepared using the freeze-thaw method, and the loading of 2.5, 5 and 7.5% w/w of ZnO NPs with respect to Ch was promoted by ultrasonication. The structural, morphological, surface and thermal properties of hydrogels loaded with ZnO NPs (HZ 2.5, HZ 5 and HZ 7

SUBMITTER: Jaimes AK 

PROVIDER: S-EPMC12846630 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature