Serological Assays to Measure Rabies Antibody Response in Equine Serum Samples.

ABSTRACT: Rabies is a neglected tropical zoonotic disease caused by rabies-virus (RV) infection and is responsible for almost 60,000 annual deaths globally, largely affecting the socio-economically disadvantaged population. Although fatality is preventable by immunization either before or after exposure with therapeutic antibodies, the high cost of prophylaxis or treatment limits their accessibility for the affected population. However, due to the almost 100% fatality rate in symptomatic individuals, almost 29 million annual vaccinations are performed, imposing high financial burden. Human transmission occurs principally through bites from infected dogs and although multiple mammalian species are permissive to RV, transmission from them or from symptomatic humans is rare. To overcome the limitations

SUBMITTER: Beniwal N 

PROVIDER: S-EPMC12846700 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature