Percutaneous coronary intervention as an independent predictor of non-target lesion progression in 1658 patients with coronary artery disease.

ABSTRACT: Rationale: Non-target lesions (NTLs) progression is common in patients with coronary artery disease (CAD). However, its predictors remain obscure. Methods: An angiographic study was conducted in patients with CAD who underwent coronary angiography twice at an interval of 6 to 30 months. NTLs were defined as lesions not treated with percutaneous coronary intervention (PCI) during the first hospitalization. A stenosis index (SI) was calculated from all NTLs in each patient. NTLs progression was defined as an increase in SI (ΔSI > 0) at follow-up. Results: Among 1658 patients recruited, 1061 (64.0%) exhibited NTL progression, with a ΔSI of 0.75 (0.40, 1.30) over a mean follow-up period of 13 months. The NTLs progression group had more males, diabetics, higher neutrophil r

SUBMITTER: Liu X 

PROVIDER: S-EPMC12846773 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature