Evolving our understanding of vitamin D, periostin levels and cardiovascular risk in the elderly: a cross sectional study.

ABSTRACT: This cross-sectional study explored how vitamin D and the protein periostin are related to the risk of heart disease in elderly individuals. Lower levels of both were linked to higher risk of heart disease. The findings suggest these markers may help identify cardiovascular (CV) risk as people age.

Purpose

Given that both vitamin D and periostin are implicated in CV health, understanding their interrelationship could provide insights into the mechanisms influencing CV risk in aging populations.

Methods

This was a cross-sectional analysis in a subgroup of elderly people from the InCHIANTI Biobank in Italy. Serum concentrations of 25-hydroxyvitamin D (25(OH)D), 1,25-dihydroxyvitamin D (1,25(OH)₂D), and periostin were measured, and their associations with both an arbi

SUBMITTER: Brandi ML 

PROVIDER: S-EPMC12847130 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature