Multimodality assessment of aortic valve area in aortic stenosis: a multicenter validation study.

ABSTRACT:

Objectives

Transthoracic echocardiography (TTE) is the standard modality for grading aortic stenosis (AS) severity. Transesophageal echocardiography (TOE) allows direct aortic valve area (AVA) planimetry (AVA_TOE), while computed tomography angiography (CTA) offers a non-invasive alternative (AVA_CTA). This study aimed to evaluate the correlation between AVA measurements across modalities and to determine a diagnostic AVA_CTA threshold for severe AS.

Methods

This retrospective study included a single-center derivation cohort of 176 patients (mean age 80.0 ± 7.7 years, 52.8% male) with moderate to severe AS who underwent full-cycle CTA, TTE, and TOE. AVA_CTA was measured by two independent raters. Correlation with AVA_TOE and

SUBMITTER: Weber C 

PROVIDER: S-EPMC12847234 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature