Failure patterns and clinical indications in early-stage follicular lymphoma: a study from the National Cancer Center in China.

ABSTRACT:

Background and purpose

The optimal management of early-stage follicular lymphoma (FL) remains an active research area, particularly in China. This retrospective cohort study examined long-term survival outcomes, recurrence patterns, and potential prognostic factors in patients with early-stage FL.

Materials and methods

We retrospectively analyzed 107 patients diagnosed with early-stage FL between 2000 and 2020 at the National Cancer Center in China. Treatment modalities included radiotherapy with or without chemoimmunotherapy or chemotherapy, chemoimmunotherapy or chemotherapy, and observation. Overall survival, progression-free survival, and lymphoma-specific survival were assessed using the Kaplan-Meier method and Cox regression models. We evaluated failure patterns, inclu

SUBMITTER: Xu C 

PROVIDER: S-EPMC12847288 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature