Changes in body water distribution and phase angle following rapid ascent to 3,680 m and their association with acute mountain sickness: a prospective cohort study.

ABSTRACT:

Background

Acute mountain sickness (AMS) is a common pathological response following rapid ascent to high altitude, and its underlying mechanisms remain incompletely understood. This study focused on investigating the early changes in body composition following acute high-altitude exposure and their association with AMS.

Methods

A prospective cohort study was conducted on healthy individuals who flew from plain (500 m) to plateau (3,680 m). Multi-frequency bioelectrical impedance analysis was used to measure body composition indicators within 24 h before and 24 h after ascent. AMS was diagnosed and its severity assessed using the Lake Louise Score System (LLSS). Comparisons of body composition changes before and after high-altitude exposure were performed, and intergroup com

SUBMITTER: Li X 

PROVIDER: S-EPMC12847375 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature