Comparative morphological analysis of the zonular apparatus in porcine, feline, and canine species.

ABSTRACT:

Purpose

To characterize and compare the morphology of the zonular apparatus in pigs, cats, and dogs to identify the optimal animal model for studying zonular pathophysiology in angle-closure mechanisms.

Methods

Porcine (n = 15), feline (n = 8), and canine (n = 4) eyes were included in this descriptive, exploratory study. Slit-lamp biomicroscopy, photography, and histological staining (Hematoxylin and Eosin, Masson's Trichrome) were utilized to evaluate structure and collagen distribution. The anterior segments of porcine, feline, and canine eyes were imaged ex vivo using ultrasound biomicroscopy (UBM). Ultrastructural morphology was further analyzed with scanning electron microscopy (SEM). Quantitative measurements were obtained with ImageJ and Ca

SUBMITTER: Lu Y 

PROVIDER: S-EPMC12847380 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature