The impact of clinical manifestations on the prognosis of diffuse large B-cell lymphoma.

ABSTRACT:

Objective

This study aimed to investigate the recurrence patterns of diffuse large B-cell lymphoma (DLBCL) and assess the significance of clinical manifestation consistency at the time of recurrence.

Methods

A total of 141 patients who were newly diagnosed with DLBCL between January 2015 and October 2024 and who initially achieved complete remission but eventually developed relapsed disease during follow-up were retrospectively identified, their recurrence circumstances were assessed, and their clinical manifestations at diagnosis and recurrence were compared. The timing of recurrence was categorized as within 1 year of postchemotherapy or later.

Results

A total of 113 (80.1%) patients presented with clinical manifestations leading to the diagnosis of recurrence. A to

SUBMITTER: Wang S 

PROVIDER: S-EPMC12847682 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature