Integrated transcriptome analysis of jejunum and liver to identify key genes and pathways associated with body weight in chickens.

ABSTRACT: This study investigates the transcriptomic variations in the jejunum and liver of Golden Montazah (GM) chickens to better understand the biological mechanisms influencing poultry growth and production. Given the vital role of poultry in fulfilling global protein demands, especially with the rising consumer preference for chicken, it is essential to explore these underlying genetic and molecular factors that drive growth. From a larger cohort of 480 GM chickens, the top 10 males in both the high-weight (HW) and low-weight (LW) groups were selected for RNA sequencing. Tissues from their jejunum and liver were collected for transcriptomic analysis. The results revealed 38 up- and 36 down-regulated genes in the jejunum, while the liver exhibited 109 up- and 74 down-regulated genes. Among these

SUBMITTER: Abdel-Kafy EM 

PROVIDER: S-EPMC12847875 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature