Geometric Microstructural Characteristics of White Matter Differentiate Patients With Facial Dyskinesias and Palsy.

ABSTRACT:

Purpose

The heterogeneous and homogeneous clinical manifestations of peripheral facial palsy (FP), hemifacial spasm (HFS), and Meige's syndrome (MS) complicate the differentiation of diagnoses for these facial motor diseases. To comprehensively investigate the white matter microstructural characteristics in patients with facial dyskinesias and palsy using geometric and integrity metrics in DTI.

Material and methods

In this prospective study conducted from September 2020 to January 2022, patients with FP, HFS, and MS, as well as sex-matched healthy control subjects, underwent 3.0 T MRI. Geometric metrics (i.e., splay, bend, twist, and total distortion) based on "Director Field Analysis" and fractional anisotropy (FA) and mean diffusivity (MD) were calculated from DTI data. Cr

SUBMITTER: Zhu H 

PROVIDER: S-EPMC12848538 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature