Synthesis of Highly Borylated 2‑Boraindanes through Multiple Borylation of Diynes.

ABSTRACT: Boraindanes, composed of aromatic two-dimensional (2D) benzene and saturated three-dimensional (3D) boracycle moieties, are considered promising candidates for bioactive compounds/probes, agents for boron neutron capture therapy, and functional materials, as they combine the photophysical properties of the 2D aromatic and the high molecular recognition ability of the 3D boracycle. However, 2-boraindanes are difficult to access due to the difficulty of constructing two unstable C-(sp³)-B bonds. Herein, we present a straightforward synthesis of highly borylated, phenanthrene-fused 2-boraindane derivatives from biphenyl-linked terminal diacetylides through a B-B bond activation strategy. This methodology provides convenient access to a range of 2-boraindanes simply by changing the

SUBMITTER: Nagashima Y 

PROVIDER: S-EPMC12848701 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature