Nickel-containing 4,4'-biphenol mixed-mode stationary phase for the separation of polyaromatic compounds, benzene derivatives and nucleotides.

ABSTRACT: A new mixed-mode hybrid stationary phase is synthesized, followed by its characterization using BET analysis, SEM, FTIR spectroscopy and EDX analysis. 4, 4'-Biphenol was esterified using ethyl chloroacetate in the presence of potassium carbonate, followed by carboxylation using ethanol/water (9 : 1 v/v%) in the presence of NaOH. The product was treated with nickel nitrate hexahydrate, resulting in the formation of nickel-containing 4,4'-biphenol. The newly synthesized stationary phase was completely characterized through ¹H-NMR, ¹³C-NMR, FTIR, EDX, FE-SEM, BET, particle size distribution, and XRD resulting in characteristics in line with proposed material and best fitting of the material to be used as the new separation media in liquid chromatography. The resultant ma

SUBMITTER: Hira 

PROVIDER: S-EPMC12848886 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature