Pediatric drug-sensitive tuberculosis treatment regimen profiles and treatment outcomes in mainland China, 2017-2022: a multi-center study.

ABSTRACT:

Background

Despite the establishment of WHO treatment guidelines for childhood tuberculosis (TB), evaluation of TB treatment regimens for children in real-world settings in China remained limited, particularly regarding treatment duration, utilization of second-line anti-TB drugs (SLDs), and adverse events. This study aimed to describe the treatment protocols for childhood TB in China.

Methods

A multi-center retrospective observational study was conducted at ten state-mandated TB referral hospitals across four regions in China during 2017-2022. Children with drug-susceptible TB who were hospitalized and under 15 years-old were enrolled. And their clinical information, including diagnosis, treatment regimen, duration, adverse events and treatment response, were collected by p

SUBMITTER: Zeng X 

PROVIDER: S-EPMC12849109 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature