Predictive value of serum homocysteine and potassium ion for short-term prognosis of patients with acute cerebral infarction following intravenous thrombolysis with recombinant tissue plasminogen activator.

ABSTRACT:

Objective

This study evaluated the predictive value of serum homocysteine (HcY) and potassium ion (K⁺) for short-term prognosis of patients with acute cerebral infarction (ACI) undergoing intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA).

Methods

Totally, 140 ACI patients receiving intravenous thrombolysis using rt-PA were finally included and classified into early neurological deterioration (END) and non-END groups. Serum levels of HcY and electrolytes were detected. The 90-day prognosis of patients after thrombolysis was analyzed. Influencing factors for END and poor short-term prognosis in rt-PA-treated ACI patients were identified using stepwise regression models. Correlations of serum HcY and K⁺ with modified Rankin sca

SUBMITTER: Pang L 

PROVIDER: S-EPMC12849246 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature