Daphnia magna diapause-interrupted embryogenesis has changes in histone modifications at H3K9.

ABSTRACT: As a key component of freshwater ecosystem, Daphnia survives environmental challenges by entering a state of developmental arrest known as diapause. Diapause is not simply a sudden halt in growth and development, but a genetically regulated program involving a sequence of coordinated developmental processes. Histone modifications, as crucial epigenetic mechanisms that regulate gene expression by altering chromatin structure, are hypothesized to play a significant role in diapause regulation. This study focuses on the acetylation (H3K9ac) and tri-methylation (H3K9me3) at the H3K9 site. Given the established roles of H3K9ac in transcriptional activation and H3K9me3 in transcriptional silencing, we hypothesize that these antagonistic modifications play regulatory roles in the diapause develop

SUBMITTER: Chen L 

PROVIDER: S-EPMC12849332 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature