Across deserts and Andes: a genetic exploration of GlyCam-1 in domestic camelids.

ABSTRACT:

Background

Lactophorin is a major whey protein in camelid milk that prevents fat globule aggregation and inhibits spontaneous lipolysis. It has also been proposed to play immunological functions, including the prevention of mastitis in lactating animals and the suppression of pathogen replication in the respiratory and gastrointestinal tracts of suckling offspring. In this study, we explore the genetic variation of the glycosylation-dependent cell adhesion molecule-1 (GlyCam-1) gene in camelids, which encodes lactophorin, and examine the functional implications of the identified polymorphisms.

Results

The regulatory regions and the complete gene were sequenced and analysed in the Old World Camelids (OWC, dromedary and bactrian) and New World Camelids (NWC, llama and alpaca)

SUBMITTER: Letaief N 

PROVIDER: S-EPMC12849490 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature