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NSOFA scores predict prolonged mechanical ventilation in neonatal respiratory distress syndrome: a retrospective cohort study.


ABSTRACT:

Background

Neonatal respiratory distress syndrome (NRDS) is one of the most common respiratory diseases in the neonatal period and a major cause of neonatal mortality. Prolonged mechanical ventilation (MV) is associated with adverse outcomes in NRDS patients, highlighting the need for effective early risk stratification tools. The Neonatal Sequential Organ Failure Assessment (nSOFA) score has emerged as a potential predictor of adverse outcomes, but its association with prolonged MV remains unclear.

Methods

This retrospective cohort study utilized data from the Medical Information Mart for Intensive Care III (MIMIC-III) database, analyzing 642 NRDS infants admitted to the neonatal intensive care unit (NICU) between 2001 and 2012. Patients were divided into two groups based o

SUBMITTER: Wang L 

PROVIDER: S-EPMC12849562 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature