Comparative evaluation of histopathological lesions and viral antigen distribution in domestic pigs and wild boar inoculated intranasally with the highly virulent ASFV genotype II strain "Armenia 2007".

ABSTRACT: African swine fever (ASF) is a devastating viral disease that affects domestic pigs (Sus scrofa domesticus) and European wild boar (Sus scrofa scrofa). A previous study indicated that wild boar were more susceptible to ASF than pigs, with shorter incubation periods and earlier onset of the disease. This follow-up study aims to compare the pathogenesis and progression of the disease between the two subspecies during the early and late stages of infection following intranasal inoculation with the highly virulent genotype II strain 'Armenia 2007'. Histopathological changes and viral antigen distribution by immunohistochemistry (IHC) were assessed over time following intranasal inoculation. Viral antigen and histological changes were detected earlier in wild boar than in pigs. In wild boar, th

SUBMITTER: Wikstrom-Lassa E 

PROVIDER: S-EPMC12849611 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature