Dataset Information
Immunophenotypic and structural signatures of severe granulation tissue in airway implant patients.
Ontology highlight
ABSTRACT:
SUBMITTER: Barbet K
PROVIDER: S-EPMC12849643 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature
Publications
Immunophenotypic and structural signatures of severe granulation tissue in airway implant patients.
Respiratory research 20260107 1
BACKGROUND: Granulation tissue formation is a frequent complication following airway implant procedures such as endobronchial valve (EBV) therapy in patients with chronic obstructive pulmonary disease (COPD). This hyperplastic response can impair implant function and clinical outcomes, yet the underlying immunological mechanisms remain poorly understood. METHODS: In a cohort of EBV patients (n = 147), we developed an optical scaling and scoring system to classify the severity of granulation tiss ...[more]
