Photocatalytic α-alkylation of carbamates with vinyl azaarenes.

ABSTRACT: An acridine-BF₃ complex is a competent photocatalyst for the α-C-H bond functionalization of N-Boc amines. Upon the photoinduced formation of the corresponding α-carbamyl radicals, these species undergo Giese-type additions to BF₃-activated vinyl azaarenes. Reactions tolerate a range of different azacycles and show good functional group compatibility.

SUBMITTER: Rickertsen DRL 

PROVIDER: S-EPMC12850520 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature