High-fructose corn syrup for managing negative energy balance in sheep.

ABSTRACT: Ketosis and its severe complication in small ruminants, pregnancy toxemia, are major metabolic disorders characterized by hypoglycemia and high blood concentrations of β-hydroxybutyrate (BHBA) resulting from negative energy balance (NEB). Although conventional treatments rely on glucogenic precursors like glycerol and propylene glycol, farmers often turn to lower-cost alternatives, including sugary soft drinks containing high-fructose corn syrup (HFCS) and carbonated water (cWater). In this study, we evaluated the relative contribution of the primary components of Coca-Cola (Coke), used here as a representative and readily accessible energy source, in mitigating NEB in sheep. Twenty-eight Afec-Assaf ewe lambs (N = 28), fasted for 48 h to induce NEB, were randomly assigned to four tr

SUBMITTER: Waiswa B 

PROVIDER: S-EPMC12850533 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature