3D MR Thermometry Using Bi-Directional Segmented EPI for Transcranial-Focused Ultrasound.

ABSTRACT:

Purpose

To evaluate the feasibility of replacing clinically utilized 2D thermometry with 3D segmented EPI-based thermometry with equivalent accuracy, precision, and scan time.

Methods

A 3D segmented EPI (segEPI) trajectory was modified to allow readouts along both the forward and reverse direction for each phase encoding line, and the sequence was integrated into the existing clinical protocol. Focused ultrasound sonications were performed in a tissue-mimicking gelatin phantom with the clinical standard scan and the proposed scan across multiple repetitions. Accuracy, precision and extent of the measured heating was compared at varied levels of zero-filled interpolation. Non-heating in vivo brain scans were performed to evaluate phase drift and precision improvements from ec

SUBMITTER: Malmberg M 

PROVIDER: S-EPMC12850574 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature