Pharmacokinetics of teicoplanin in paediatric patients-A systematic review of current literature.

ABSTRACT:

Background and objective

Teicoplanin is commonly used in children to treat gram-positive infections and is sometimes used off-label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment. This systematic review aims to summarize and evaluate reported PK data and target attainment, identify PK variations and provide dosing recommendations when available.

Methods

A systematic literature search was performed in PubMed and Embase, following PRISMA 2020 guidelines. Included studies were randomized controlled trials, nonrandomized controlled trials or prospective/retrospective cohort studies, published up to December 2024,

SUBMITTER: Wijnen NE 

PROVIDER: S-EPMC12850597 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature