Free-Breathing, 3D Cardiac Magnetic Resonance Elastography for Myocardial Stiffness Mapping.

ABSTRACT:

Purpose

Magnetic resonance elastography (MRE) of the heart has predominantly utilized breath-held acquisitions with limited anatomic coverage. This work investigates the feasibility of 3D, free-breathing cardiac MRE.

Methods

A 3D hybrid radial and EPI acquisition is utilized and combined with retrospective binning of k-space via physiologic monitoring, iterative reconstruction, MRE processing and inversions, and post-processing specialized for cardiac imaging.

Results

Feasibility of free-breathing stiffness mapping of the left ventricular myocardium was demonstrated in 11 participants. Myocardial stiffness estimates were obtained throughout the left ventricle for seven temporal states of the cardiac cycle. Stiffness estimates were presented in participant-specific ima

SUBMITTER: Meyer NK 

PROVIDER: S-EPMC12850599 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature