Free-Breathing Multi-Slice Co-Registered Cardiac T1, T2, and ADC Mapping With Spin-Echo Echo Planar Imaging.

ABSTRACT:

Purpose

To develop a free-breathing method for multi-slice co-registered cardiac T1, T2, and ADC maps using single-shot spin-echo echo planar imaging (SE-EPI).

Methods

T1, T2, and diffusion weighted images in five slices were acquired with SE-EPI readouts during free breathing using interleaved acquisition of slices, non-selective inversion recovery, varying echo times (TE), and second-order motion-compensated diffusion gradients in three orthogonal directions with different b values. All images were registered to a single target image followed by parameter fitting to generate co-registered T1/T2/ADC maps. This approach was evaluated in phantom measurements, 13 healthy volunteers, two myocardial infarction (MI) swine, and two cardiac amyloidosis (CA) patients by comparison t

SUBMITTER: Mai D 

PROVIDER: S-EPMC12850609 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature