Evaluation of Partial Volume Correction Techniques for Sodium MRI of the Achilles Tendon.

ABSTRACT:

Purpose

To evaluate partial volume correction (PVC) techniques for sodium MRI of the Achilles tendon in situ and in vivo.

Methods

Five PVC methods were evaluated including a volume ratio of the proton and sodium segmentations (PSSR), a modified least trimmed square (3D-mLTS) linear regression, a geometric transfer matrix (GTM) approach, a single target correction (STC), and a novel estimated single target correction (eSTC). Their performance was tested using simulated data and 3 T MR data of two volunteers' Achilles tendons acquired at different resolutions: 1.5, 2.0, 3.0, and 4.5 mm³. Since there was no in vivo ground truth, the highest-resolution apparent tissue sodium contents (aTSC) were used.

Results

In the simulation, all PVC methods reduced the diffe

SUBMITTER: Moller R 

PROVIDER: S-EPMC12850615 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature