Spatial and racial/ethnic disparities in cardiovascular mortality attributable to PM_2.5 components in the contiguous United States.

ABSTRACT: Long-term exposure to fine particulate matter (PM_2.5) is a well-established risk factor for cardiovascular disease (CVD) mortality, yet the contributions of its components remain unclear, particularly across geographic regions and racial/ethnic groups. We extended the generalized weighted quantile sum regression model by incorporating two-way fixed effects (gWQS-feglm) to quantify PM_2.5 component-attributable CVD deaths across the contiguous United States. PM_2.5 component-attributable CVD deaths declined from 42,200 (28,200,57,600) in 2001 to 23,500 (15,700,32,100) in 2020, driven by ammonium (NH₄⁺) and sulfate (SO₄^2-) reductions. In 2020, high-attributable-mortality regions remained and regional disparities in PM

SUBMITTER: Hu Y 

PROVIDER: S-EPMC12851041 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature