Risk factors, outcomes, and early prediction of cardiac surgery-associated acute kidney injury: a post hoc subgroup analysis of the Epidemiology of Surgery Associated Acute Kidney Injury study.

ABSTRACT:

Background

Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and important complication. The risk factors for CSA-AKI remain poorly described. We aimed to identify risk factors for CSA-AKI and develop a risk score for persistent CSA-AKI.

Methods

We performed a post hoc subgroup analysis restricted to patients who underwent cardiac surgery within the Epidemiology of Surgery Associated Acute Kidney Injury (EPIS-AKI) study. CSA-AKI was defined as AKI (according to the Kidney Disease: Improving Global Outcomes criteria) within 72 h after surgery. Persistent CSA-AKI was defined as CSA-AKI lasting >48 h. We performed multivariable logistic regression analyses to identify risk factors for CSA-AKI and related outcomes.

Results

The original EPIS-AKI study in

SUBMITTER: Strauß C 

PROVIDER: S-EPMC12851876 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature