The Influence of Bariatric Surgery on Serum Level of Nesfatin-1: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Obesity is an escalating worldwide health issue, and bariatric surgery has demonstrated efficacy as a strategy for substantial weight reduction and metabolic improvement. Nesfatin-1, an anorexigenic peptide, is associated with appetite control and energy balance; nevertheless, its response following bariatric surgery is variable. This meta-analysis assesses the effects of bariatric surgery on BMI and nesfatin-1 concentrations in individuals with obesity.

Methods

A comprehensive literature search was performed in PubMed, Scopus, Embase, and Web of Science, according to PRISMA criteria. Included were studies examining pre- and post-surgical alterations in BMI and nesfatin-1 levels. A random-effects meta-analysis was conducted to evaluate aggregated effect sizes, het

SUBMITTER: Bidares M 

PROVIDER: S-EPMC12852053 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature