Persistent inequities in neonatal encephalopathy: a 30-year global burden analysis (1990-2021).

ABSTRACT:

Background

Neonatal encephalopathy (NE) remains a significant cause of mortality and long-term disability in children under five, with pronounced global disparities in incidence and outcomes despite available interventions. This study aims to identify inequalities in the NE burden, with the goal of informing strategies to promote health equity and well-being in children.

Methods

Using data from the GBD 2021 study, we analyzed NE incidence, mortality, and disability-adjusted life years (DALYs) across 204 countries from 1990 to 2021. Data were assessed by age, sex, region, and Sociodemographic Index (SDI). Trends were quantified using estimated annual percentage change (EAPC).

Result

Globally, NE incidence declined by 18.1%, mortality by 31.6%, and DALYs by 27.7%

SUBMITTER: Yuan Y 

PROVIDER: S-EPMC12852322 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature