Hormonal regulation and reproductive improvement with adjunctive Zishen Yutai Pill in polycystic ovary syndrome: a systematic review with meta-analysis.

ABSTRACT:

Objective

To systematically evaluate the therapeutic efficacy and safety of Zishen Yutai Pill (ZYP) as an adjunctive treatment for women with polycystic ovary syndrome (PCOS) through systematic review and meta-analysis of randomized controlled trials.

Materials and methods

A systematic review and meta-analysis were conducted in accordance with PRISMA guidelines. Seven major databases, including PubMed, Embase, Web of Science, Cochrane Library, CNKI, VIP, and Wan Fang Database, were searched from inception through March 1, 2025. Randomized controlled trials comparing ZYP combined with Western medicines vs. Western medicines alone were included.

Results

Eighteen randomized controlled trials encompassing 1,751 participants with PCOS met the inclusion criteria. Meta-analy

SUBMITTER: Lu X 

PROVIDER: S-EPMC12852447 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature